Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199079 | 0.86 | SMN1; SMN2 (0.39) | HSD17B10SMN1; SMN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL4717203 | 0.80 | GAA (0.38) | SMN1; SMN2ALDH1A1LMNATSHRUSP2 | |
| SCHEMBL11710279 | 0.76 | GAA (0.43) | GAA | |
| SCHEMBL6188489 | 0.73 | SMN1; SMN2 (0.41) | HSD17B10SMN1; SMN2ALDH1A1LMNAPKM | |
| SCHEMBL9934042 | 0.73 | GAA (0.43) | GAA | |
| SCHEMBL8642184 | 0.71 | KEAP1 (0.41) | HSD17B10SMN1; SMN2ALDH1A1MAPK1GAA | |
| SCHEMBL8696697 | 0.70 | GAA (0.43) | GAA | |
| SCHEMBL8552747 | 0.70 | GAA (0.43) | GAA | |
| SCHEMBL8900868 | 0.69 | GAA (0.38) | SMN1; SMN2ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL4481007 | 0.68 | MAPT (0.42) | ALDH1A1MAPK1GAAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004741-A | Cholecystokinin(CCK); Treating Disorders Of The Gastrointestinal Tract, Central Nervous System And Of The Appetite Of Animals | MERCK & CO., INC. (US) | 1991-04-02 | — | — | US | disclosed |
| US-4820834-A | Benzodiazepine analogs | MERCK & CO., INC. (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0284256-A1 | Benzodiazepine analogs | MERCK & CO. INC. (US) | 1988-09-28 | — | — | EP | disclosed |