Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867273 | 0.89 | DRD4 (0.65) | SLC6A12DRD4DRD2DRD3 | |
| SCHEMBL9866864 | 0.88 | DRD4 (0.55) | SIGMAR1POLBMAPK1MAPTPKM | |
| SCHEMBL9868364 | 0.85 | SIGMAR1 (0.61) | SIGMAR1POLBMAPK1SLC6A12TMEM97 | |
| Fumaric Acid SCHEMBL9866524 | 0.85 | CYP3A4 (0.64) | SLC6A12DRD4DRD2DRD3 | |
| Fumaric Acid SCHEMBL9866529 | 0.85 | CYP3A4 (0.64) | SLC6A12DRD4DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL9867074 | 0.84 | SIGMAR1 (0.60) | SIGMAR1POLBMAPK1SLC6A12TMEM97 | |
| SCHEMBL9866178 | 0.82 | MLNR (0.42) | SIGMAR1POLBMAPK1MAPTPKM | |
| SCHEMBL9867056 | 0.81 | DRD4 (0.55) | SLC6A12DRD4DRD2DRD3 | |
| SCHEMBL9867302 | 0.81 | DRD4 (0.57) | DRD4DRD2DRD3 | |
| SCHEMBL9866907 | 0.79 | DRD4 (0.53) | DRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026858-A | Used for treating nausea, vomating, gastrointestinal disorders and centarl nervous system | WALTON S.A. (ES) | 1991-06-25 | — | — | US | disclosed |