Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17704770 | 0.81 | FAAH (0.52) | ATMFAAHPHGDHMGLLALDH1A1 | |
| SCHEMBL12745101 | 0.80 | ATM (0.53) | ATMFAAHPHGDHMGLLALDH1A1 | |
| SCHEMBL1299863 | 0.78 | FAAH (0.45) | ATMFAAHPHGDHMGLLALDH1A1 | |
| SCHEMBL1515471 | 0.75 | ATM (0.47) | ATMFAAHPHGDHMGLLALDH1A1 | |
| SCHEMBL27862797 | 0.74 | FAAH (0.45) | ATMFAAHPHGDHMGLLALDH1A1 | |
| SCHEMBL2303666 | 0.73 | NPC1 (0.39) | ALDH1A1RAB9APOLBNPC1GAA | |
| SCHEMBL967457 | 0.73 | FAAH (0.48) | ATMFAAHPHGDHMGLLALDH1A1 | |
| SCHEMBL4086065 | 0.72 | FAAH (0.44) | ATMFAAHPHGDHMGLLALDH1A1 | |
| SCHEMBL1633452 | 0.72 | FAAH (0.44) | ATMFAAHPHGDHMGLLALDH1A1 | |
| SCHEMBL4085292 | 0.72 | FAAH (0.44) | ATMFAAHPHGDHMGLLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051517-A | Reacting a chloroformidine hydrochloride with an oxamohydrazide, forming bonds between carbon and nitrogen and cyclization | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | disclosed |