Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.53 |
| ▸ | TERT | O14746 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866277 | 0.98 | TBXAS1 (0.56) | TBXAS1TERTHRH4HRH3TAAR1 | |
| SCHEMBL413787 | 0.94 | TAAR1 (0.50) | TBXAS1TERTHRH4HRH3TAAR1 | |
| SCHEMBL2148633 | 0.86 | TAAR1 (0.49) | TBXAS1TERTTAAR1ALOX15HTR1A | |
| SCHEMBL3431746 | 0.85 | TBXAS1 (0.66) | TBXAS1TERTTAAR1ALOX15HTR1A | |
| SCHEMBL28062565 | 0.83 | TBXAS1 (0.69) | TBXAS1TERTTAAR1ALOX15HTR1A | |
| SCHEMBL503743 | 0.83 | TBXAS1 (0.69) | TBXAS1TERTTAAR1ALOX15HTR1A | |
| SCHEMBL23397872 | 0.82 | TAAR1 (0.50) | TBXAS1TERTTAAR1ALOX15HTR1A | |
| SCHEMBL9777191 | 0.81 | TBXAS1 (0.60) | TBXAS1TERTTAAR1ALOX15HTR1A | |
| SCHEMBL3030817 | 0.80 | TBXAS1 (0.56) | TBXAS1TERTTAAR1ALOX15HTR1A | |
| SCHEMBL89096 | 0.80 | TBXAS1 (0.56) | TBXAS1TERTTAAR1ALOX15HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011838-A | Antiallergens, antihistamines | DOMPE FARMACEUTICI S.P.A. (IT) | 1991-04-30 | — | — | US | disclosed |
| EP-0397615-A2 | Pharmacologically active 2-substituted 3-(2-ethoxyethyl) imidazo [4,5-b] pyridines and pharmaceutical compositions containing them | DOMPE' FARMACEUTICI S.p.A. (IT) | 1990-11-14 | — | — | EP | disclosed |