Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.48 |
| ▸ | HRH2 | P25021 | 3/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ATP4A | P20648 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867214 | 1.00 | L3MBTL1 (0.59) | L3MBTL1SMN1; SMN2SLC47A1HRH2HRH4 | |
| Bromide SCHEMBL10874304 | 0.98 | L3MBTL1 (0.58) | L3MBTL1SMN1; SMN2SLC47A1HRH2HRH4 | |
| SCHEMBL9865686 | 0.84 | L3MBTL1 (0.56) | L3MBTL1SMN1; SMN2SLC47A1HRH2HRH4 | |
| SCHEMBL9868881 | 0.84 | L3MBTL1 (0.56) | L3MBTL1SMN1; SMN2SLC47A1HRH2HRH4 | |
| SCHEMBL9865226 | 0.84 | L3MBTL1 (0.56) | L3MBTL1SMN1; SMN2SLC47A1HRH2HRH4 | |
| Bromide SCHEMBL10873394 | 0.83 | L3MBTL1 (0.55) | L3MBTL1SMN1; SMN2SLC47A1HRH2HRH4 | |
| SCHEMBL11003643 | 0.82 | L3MBTL1 (0.40) | L3MBTL1SMN1; SMN2SLC47A1HRH2HRH4 | |
| Bromide SCHEMBL11004918 | 0.81 | L3MBTL1 (0.39) | L3MBTL1SMN1; SMN2SLC47A1HRH2HRH4 | |
| SCHEMBL11005817 | 0.77 | L3MBTL1 (0.34) | L3MBTL1HRH4HRH3MEN1LMNA | |
| SCHEMBL9574691 | 0.76 | L3MBTL1 (0.97) | L3MBTL1SMN1; SMN2SLC47A1HRH2HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021431-A | H-1 antagonist, h-2 agonist for treating hypertension, cardiac disease or arterial occlusion | HEUMANN PHARMA GMBH & CO. (DE) | 1991-06-04 | — | — | US | disclosed |