Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylformamide SCHEMBL1835955 | 0.91 | — | — | |
| Dimethylformamide SCHEMBL28269265 | 0.91 | TSHR (0.64) | TSHRUSP2ALOX15MAPT | |
| Di(Hydroxyethyl)Ether SCHEMBL7942574 | 0.85 | TSHR (0.48) | TSHRMAPT | |
| Dimethylformamide SCHEMBL27315908 | 0.84 | TSHR (0.64) | TSHR | |
| Dimethylformamide SCHEMBL2145949 | 0.84 | — | — | |
| Triethylene Glycol SCHEMBL27679778 | 0.83 | MEN1 (0.50) | TSHRMAPT | |
| Ether SCHEMBL18985182 | 0.81 | TSHR (0.45) | TSHRUSP2ALOX15 | |
| Dimethylformamide SCHEMBL8193215 | 0.81 | TSHR (0.45) | TSHRUSP2ALOX15 | |
| Dimethylformamide SCHEMBL27730194 | 0.81 | TSHR (0.69) | TSHR | |
| Dimethylformamide SCHEMBL28224916 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994612-A | Intermediates for dihydropyridine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-02-19 | — | — | US | disclosed |