Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL7942574

CN(C)C=O.COC.OCCOCCO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
MAPK1 P28482 1/20 0.48
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 1/20 0.40
THRB P10828 1/20 0.37
HTT P42858 1/20 0.37
MAPT P10636 1/20 0.37
APP P05067 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triethylene Glycol SCHEMBL27679778 0.98 MEN1 (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL10985919 0.95 TSHR (0.53) TSHRMAPK1MEN1KMT2AALDH1A1
Triethylene Glycol SCHEMBL9486662 0.93 MEN1 (0.55) TSHRMAPK1MEN1KMT2AALDH1A1
Tetraethylene Glycol SCHEMBL10390998 0.93 MEN1 (0.55) TSHRMAPK1MEN1KMT2AALDH1A1
Triethylene Glycol SCHEMBL9487295 0.89 MEN1 (0.46) TSHRMAPK1MEN1KMT2AALDH1A1
Dimethylformamide SCHEMBL28261531 0.89 MEN1 (0.46) TSHRMAPK1MEN1KMT2AALDH1A1
Dimethylformamide SCHEMBL9867429 0.85 TSHR (0.53) TSHRMAPT
Diethylene Glycol Monoethyl Ether SCHEMBL10007009 0.85 ALDH1A1 (0.58) TSHRMAPK1MEN1KMT2AALDH1A1
2-Ethoxyethanol SCHEMBL9321382 0.84 ALDH1A1 (0.64) TSHRMAPK1MEN1KMT2AALDH1A1
Dimethylformamide SCHEMBL8193215 0.83 TSHR (0.45) TSHRMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6190731-B1 FORMING A HIGHLY DISPERSED COLLOIDAL SUSPENSION OF PARTICLES, ADDING TO THE SUSPENSION AN ENCAPSULANT MATERIAL TO ENCAPSULATE INDIVIDUAL PARTICLES, AND ISOLATING FROM SAID SUSPENSION INDEPENDENT ENCAPSULATED PARTICLES Tecle, Berhan 2001-02-20 US claimed
US-5922403-A ADDING ENCAPSULANT TO HIGHLY DISPERSED COLLOIDAL SUSPENSION OF SOLID PARTICLES TO ENCAPSULATE INDIVIDUAL PARTICLES; AGGLOMERATING; ISOLATING ENCAPSULATED PARTICLES BY SEPARATION FROM SOLVENT LAYER TECLE, BERHAN 1999-07-13 US claimed
EP-0917501-A1 METHOD FOR ISOLATING ULTRAFINE AND FINE PARTICLES AND RESULTING PARTICLES Tecle, Berhan (US) 1999-05-26 EP claimed
WO-1997033713-A1 METHOD FOR ISOLATING ULTRAFINE AND FINE PARTICLES AND RESULTING PARTICLES TECLE BERHAN (US) 1997-09-18 WO claimed