Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866266 | 0.96 | MCHR1 (0.42) | ALDH1A1MCHR1MAPTGAAL3MBTL1 | |
| SCHEMBL9867236 | 0.95 | MCHR1 (0.44) | ALDH1A1MCHR1MAPTGAAL3MBTL1 | |
| SCHEMBL9865646 | 0.92 | MCHR1 (0.40) | ALDH1A1MCHR1MAPTGAATHRB | |
| SCHEMBL9867705 | 0.91 | MCHR1 (0.41) | ALDH1A1MCHR1MAPTGAAL3MBTL1 | |
| SCHEMBL9865428 | 0.90 | MCHR1 (0.38) | ALDH1A1MCHR1MAPTMEN1KMT2A | |
| SCHEMBL9866270 | 0.89 | MCHR1 (0.42) | ALDH1A1MCHR1MAPTTHRBMEN1 | |
| SCHEMBL9865707 | 0.88 | MCHR1 (0.38) | ALDH1A1MCHR1MAPTGAAMEN1 | |
| SCHEMBL9866420 | 0.88 | MCHR1 (0.43) | ALDH1A1MCHR1MAPTGAAL3MBTL1 | |
| SCHEMBL9602846 | 0.88 | MCHR1 (0.41) | ALDH1A1MCHR1MAPTMEN1KMT2A | |
| SCHEMBL9603115 | 0.86 | MCHR1 (0.48) | ALDH1A1MCHR1MAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |