Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867236 | 0.92 | MCHR1 (0.44) | MCHR1ALDH1A1LMNAHPGDALOX12 | |
| SCHEMBL9866266 | 0.90 | MCHR1 (0.42) | MCHR1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL9866270 | 0.90 | MCHR1 (0.42) | MCHR1ALDH1A1LMNAMAPTHRH3 | |
| SCHEMBL9866420 | 0.89 | MCHR1 (0.43) | MCHR1ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL9865646 | 0.88 | MCHR1 (0.40) | MCHR1ALDH1A1MAPTSMN1; SMN2HRH3 | |
| SCHEMBL9867683 | 0.88 | ALDH1A1 (0.41) | MCHR1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL9603115 | 0.87 | MCHR1 (0.48) | MCHR1ALDH1A1LMNAHPGDALOX12 | |
| SCHEMBL9865707 | 0.87 | MCHR1 (0.38) | MCHR1ALDH1A1LMNAHPGDALOX12 | |
| SCHEMBL9602706 | 0.87 | HRH3 (0.38) | ALDH1A1LMNAHPGDALOX12MAPT | |
| SCHEMBL9867705 | 0.87 | MCHR1 (0.41) | MCHR1ALDH1A1MAPTSMN1; SMN2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351435-B1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |