Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | PKM | P14618 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | GFER | P55789 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11452978 | 0.86 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDMAPTPKM | |
| SCHEMBL7977954 | 0.79 | ALDH1A1 (0.73) | ALDH1A1KDM4EHPGDMAPTPKM | |
| SCHEMBL11621135 | 0.77 | ALDH1A1 (0.65) | ALDH1A1KDM4EHPGDMAPTPKM | |
| SCHEMBL27990409 | 0.77 | ALDH1A1 (0.75) | ALDH1A1KDM4EHPGDMAPTPKM | |
| SCHEMBL11504470 | 0.76 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDMAPTPKM | |
| SCHEMBL11736792 | 0.76 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDMAPTPKM | |
| SCHEMBL5536394 | 0.76 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDMAPTPKM | |
| SCHEMBL2056342 | 0.76 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDMAPTPKM | |
| SCHEMBL11505498 | 0.76 | CYP3A4 (0.66) | ALDH1A1KDM4EHPGDMAPTPKM | |
| SCHEMBL9867707 | 0.75 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3095172-A | — | — | None | — | — | JP | disclosed |
| JP-H0395172-A | USE OF 5-PHENYL-2-FRAN KETONE AS ANTIEPILEPTIC | NORWICH EATON PHARMACEUT INC | 1991-04-19 | — | — | JP | disclosed |
| US-4035394-A | 5-Phenyl-2-furanyl-oxo or-hydroxy alkanoic acids and ethyl esters as gastric acid antisecretory agents | MORTON-NORWICH PRODUCTS, INC. (US) | 1977-07-12 | — | — | US | disclosed |