Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.76 |
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
| ▸ | HTT | P42858 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.66 |
| ▸ | RAPGEF3 | O95398 | 11/20 | 0.62 |
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.62 |
| ▸ | ALB | P02768 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | NPY1R | P25929 | 1/20 | 0.53 |
| ▸ | NPY2R | P49146 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865909 | 1.00 | MAPT (0.76) | MAPTSMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL9867790 | 0.87 | MAPT (0.70) | MAPTSMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL3678595 | 0.87 | MAPT (0.70) | MAPTSMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL9868712 | 0.85 | MAPT (0.67) | MAPTSMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL9868710 | 0.85 | MAPT (0.67) | MAPTSMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL9868180 | 0.82 | MAPT (0.65) | MAPTSMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL9868178 | 0.82 | MAPT (0.65) | MAPTSMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL31597668 | 0.80 | MEN1 (0.64) | MAPTSMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL38652827 | 0.80 | MEN1 (0.64) | MAPTSMN1; SMN2LMNAHTTMEN1 | |
| Carbonyl Cyanide M-Chlorophenylhydrazone SCHEMBL29353613 | 0.80 | MAPT (1.00) | MAPTSMN1; SMN2LMNAHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412211-A1 | Cancer therapy system | THERAPEUTICAL SYSTEMS CORPORATION (US) | 1991-02-13 | — | — | EP | disclosed |
| US-4935450-A | Cancer therapy system for effecting oncolysis of malignant neoplasms | THERAPEUTICAL SYSTEMS CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |
| US-4724234-A | ADMINISTERING NUTRITIONAL REGIMEN AND AGENTS WHICH UNCOUPLE OXIDATIVE PHOSPHORYLATION | THERAPEUTICAL SYSTEMS CORP. (US) | 1988-02-09 | — | — | US | disclosed |