Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.59 |
| ▸ | NPY1R | P25929 | 1/20 | 0.59 |
| ▸ | NPY2R | P49146 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868180 | 1.00 | MAPT (0.65) | MAPTNPSR1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL922713 | 0.84 | MAPT (0.81) | MAPTNPSR1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL922712 | 0.84 | MAPT (0.81) | MAPTNPSR1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL16291929 | 0.83 | MAPT (0.58) | MAPTNPSR1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL16291927 | 0.83 | MAPT (0.58) | MAPTNPSR1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL9868264 | 0.83 | MAPT (0.58) | MAPTNPSR1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL9868268 | 0.83 | MAPT (0.58) | MAPTNPSR1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL9865909 | 0.82 | MAPT (0.76) | MAPTNPSR1GAASMN1; SMN2HTT | |
| SCHEMBL9868037 | 0.82 | MAPT (0.76) | MAPTNPSR1GAASMN1; SMN2HTT | |
| SCHEMBL11197606 | 0.77 | MAPT (0.69) | MAPTNPSR1GAAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412211-A1 | Cancer therapy system | THERAPEUTICAL SYSTEMS CORPORATION (US) | 1991-02-13 | — | — | EP | disclosed |
| US-4935450-A | Cancer therapy system for effecting oncolysis of malignant neoplasms | THERAPEUTICAL SYSTEMS CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |
| US-4724234-A | ADMINISTERING NUTRITIONAL REGIMEN AND AGENTS WHICH UNCOUPLE OXIDATIVE PHOSPHORYLATION | THERAPEUTICAL SYSTEMS CORP. (US) | 1988-02-09 | — | — | US | disclosed |