SCHEMBL9868040

SCHEMBL9868040

O=C=C1C=CC=CC1C(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL239044 0.83
Water SCHEMBL27822730 0.82
Hydrochloric Acid SCHEMBL27545669 0.82
Hydrochloric Acid SCHEMBL5751359 0.82
Hydrazine SCHEMBL28208339 0.80
SCHEMBL27258058 0.79
SCHEMBL4554819 0.77 ALDH1A1 (0.33)
SCHEMBL27967494 0.76
SCHEMBL5708278 0.74
Pyridine SCHEMBL10748685 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166115-A Monomeric and multimeric anti-HBV agents 埃默里大学 2021-07-23 CN disclosed
US-RE33533-E Skin disorders CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD) (FR) 1991-02-05 US disclosed
US-4874747-A DERMATOLOGY CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD) (FR) 1989-10-17 US disclosed
US-4474968-A Cyclopentene derivatives THE UPJOHN COMPANY (US) 1984-10-02 US disclosed
US-4458083-A ANTITUMOR AGENTS, MICROBIOCIDES THE UPJOHN COMPANY (US) 1984-07-03 US disclosed
US-4458084-A Cyclopentene derivatives THE UPJOHN COMPANY (US) 1984-07-03 US disclosed
US-4458089-A ANTITUMOR AGENTS, MICROBIOCIDES THE UPJOHN COMPANY (US) 1984-07-03 US disclosed
US-4455430-A ANTITUMOR AGENTS, MICROCIDES THE UPJOHN COMPANY (US) 1984-06-19 US disclosed
US-RE31578-E ANTITUMOR AGENTS, BACTERICIDES THE UPJOHN COMPANY (US) 1984-05-01 US disclosed
US-4298744-A CHLORINATION OF ISOMERIC ANALOG THE UPJOHN COMPANY (US) 1981-11-03 US disclosed
US-4275214-A ANALOGS OF TRICHOLOMIC ACID USEFUL AS INTERMEDIATES IN THE PREPARATION OF AT-125 THE UPJOHN COMPANY (US) 1981-06-23 US disclosed
US-4256898-A INTERMEDIATES FOR MAKING (ALPHAS, 5S)-ALPHA-AMINO-3-CHLORO-2-ISOXAZOLINE-5-ACETIC ACID (AT-125) THE UPJOHN COMPANY (US) 1981-03-17 US disclosed
US-4043976-A N,N'-DIBENZOYLHYDRAZINE DERIVATIVE UBE INDUSTRIES, LTD. (JA) 1977-08-23 US disclosed