Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653325 | 0.80 | BRD4 (0.39) | MAPTALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL4846663 | 0.78 | KDM4E (0.41) | MAPTALDH1A1KMT2ARECQLMCL1 | |
| SCHEMBL31177224 | 0.78 | TP53 (0.53) | MAPTALDH1A1ALOX15KMT2AL3MBTL1 | |
| SCHEMBL7656644 | 0.78 | HIF1A (0.41) | VCAM1MAPTALDH1A1HTTKMT2A | |
| SCHEMBL30841549 | 0.78 | HIF1A (0.41) | VCAM1MAPTALDH1A1HTTKMT2A | |
| SCHEMBL7659144 | 0.78 | MAPT (0.46) | VCAM1MAPTALDH1A1CYP1A2KMT2A | |
| SCHEMBL29375067 | 0.78 | KDM4E (0.41) | MAPTALDH1A1KMT2ARECQLMCL1 | |
| SCHEMBL9404841 | 0.78 | TP53 (0.53) | MAPTALDH1A1ALOX15KMT2AL3MBTL1 | |
| SCHEMBL22463118 | 0.78 | TDP1 (0.40) | MAPTALDH1A1ALOX15KMT2AMEN1 | |
| SCHEMBL4657132 | 0.76 | TSHR (0.42) | MAPTALDH1A1HTTKMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5061795-A | ANTITUMOR AGENTS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1991-10-29 | — | — | US | disclosed |