SCHEMBL9868059

SCHEMBL9868059

FC(F)(F)C(F)(F)C(F)(F)C(I)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9867846 0.88 LMNA (0.32) LMNA
SCHEMBL1921501 0.74
Perflubutane SCHEMBL111514 0.73 LMNA (0.54) LMNATHRB
Perflubutane SCHEMBL9051673 0.73 LMNA (0.54) LMNATHRB
SCHEMBL47999 0.72 LMNA (0.39) LMNATHRB
SCHEMBL6052598 0.72 LMNA (0.39) LMNATHRB
SCHEMBL2850706 0.72 LMNA (0.39) LMNATHRB
SCHEMBL248899 0.69 LMNA (0.44) LMNATHRB
SCHEMBL1829883 0.69 LMNA (0.44) LMNATHRB
SCHEMBL1727233 0.69 LMNA (0.44) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113493450-A Ligand compound, preparation method thereof and application thereof in asymmetric reaction 中国科学院福建物质结构研究所 2021-10-12 CN disclosed
CN-112794788-B Method for synthesizing fluoroisobutylene by using hexafluoropropylene as starting material 泉州宇极新材料科技有限公司 2021-07-09 CN disclosed
CN-112794788-A Method for synthesizing fluoroisobutylene by using hexafluoropropylene as starting material 北京宇极科技发展有限公司 2021-05-14 CN disclosed
EP-0228701-B1 2-IODO-PERFLUORO-2-METHYLAKANES, PROCESS FOR THEIR PRODUCTION AND THEIR APPLICATION HOECHST AKTIENGESELLSCHAFT (DE) 1991-02-27 EP disclosed
US-4760205-A 2-iodo-perfluoro-2-methylalkanes, processes for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-26 US disclosed
EP-0228701-A2 2-Iodo-perfluoro-2-methylakanes, process for their production and their application HOECHST AKTIENGESELLSCHAFT (DE) 1987-07-15 EP disclosed