Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9865080 | 0.98 | SIGMAR1 (0.71) | SIGMAR1 | |
| SCHEMBL11775261 | 0.92 | SIGMAR1 (0.63) | SIGMAR1 | |
| SCHEMBL4870895 | 0.79 | CHRM2 (0.60) | SIGMAR1 | |
| SCHEMBL29937379 | 0.78 | SIGMAR1 (0.50) | SIGMAR1 | |
| Ammonia Solution, Strong SCHEMBL8187341 | 0.78 | CHRM2 (0.58) | SIGMAR1 | |
| SCHEMBL1723411 | 0.78 | CHRM2 (0.58) | SIGMAR1 | |
| SCHEMBL5728905 | 0.78 | CHRM2 (0.58) | SIGMAR1 | |
| SCHEMBL20328234 | 0.76 | SIGMAR1 (0.51) | SIGMAR1 | |
| SCHEMBL10475095 | 0.76 | CHRM2 (0.51) | SIGMAR1 | |
| SCHEMBL10211436 | 0.76 | SIGMAR1 (0.48) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992546-A | Process for preparing 6,8-diazabicyclo[3.2.2]nonane derivatives | WARNER-LAMBERT COMPANY (US) | 1991-02-12 | — | — | US | disclosed |
| US-4968799-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1990-11-06 | — | — | US | disclosed |
| US-4962108-A | A QUIN-4-ONE HAVING THE FOLLOWING RING SUBSTITUENTS; 1-ALKYL OR PHENYL, 3-CARBOXY DERIVATIVE, 6-FLUORO AND 8-BRIDGED N-HETEROCYCLIC RING | WARNER-LAMBERT COMPANY (US) | 1990-10-09 | — | — | US | disclosed |
| US-4923879-A | CARBOXYLIC ACID DERIVATIVES WITH BRIDGED SIDECHAINS | WARNER-LAMBERT COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| EP-0305744-A2 | Quinoline, naphthyridine and benzoxazine-carboxylic acid derivatives and their use as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-03-08 | — | — | EP | disclosed |