Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 5/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL10384330 | 0.91 | NISCH (0.44) | NISCH | |
| SCHEMBL10906535 | 0.87 | DRD2 (0.43) | NISCH | |
| SCHEMBL10758788 | 0.83 | NISCH (0.47) | NISCHMAOAMAOB | |
| SCHEMBL9868142 | 0.81 | — | — | |
| SCHEMBL10907467 | 0.80 | NISCH (0.46) | NISCH | |
| SCHEMBL10383763 | 0.77 | — | — | |
| SCHEMBL9867578 | 0.77 | — | — | |
| SCHEMBL8944664 | 0.69 | NISCH (0.48) | NISCHMAOAMAOB | |
| SCHEMBL4418509 | 0.68 | GAA (0.61) | — | |
| SCHEMBL8944813 | 0.68 | NISCH (0.47) | NISCHMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017584-A | Antidepressant 2-(4,5-dihydro-1H-imidazolyl)-dihydro-1H-indoles, -1,2,3,4-tetrahydroquinolines and -1H-indoles, and methods of use thereas | STERLING DRUG INC. (US) | 1991-05-21 | — | — | US | claimed |
| US-4598086-A | ANTIDERPRESSANTS; HYPERTENSIVE AGENTS | SYNTHELABO, (FR) | 1986-07-01 | — | — | US | disclosed |