Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708566 | 0.82 | MAPT (0.57) | MAPTNPC1POLBRAB9AKDM4E | |
| SCHEMBL4555454 | 0.78 | NPC1 (0.74) | MAPTNPC1POLBRAB9AKDM4E | |
| SCHEMBL679708 | 0.76 | KMT2A (0.61) | MAPTNPC1POLBRAB9AKDM4E | |
| SCHEMBL4649312 | 0.71 | NPC1 (0.49) | MAPTNPC1POLBRAB9AENPP2 | |
| SCHEMBL725810 | 0.71 | ALDH1A1 (0.75) | MAPTNPC1POLBRAB9AKDM4E | |
| SCHEMBL13159758 | 0.68 | NPC1 (0.48) | NPC1POLBRAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL4526983 | 0.68 | NPC1 (0.67) | MAPTNPC1POLBRAB9AKDM4E | |
| SCHEMBL4508303 | 0.68 | MEN1 (0.55) | MAPTNPC1POLBRAB9AKDM4E | |
| SCHEMBL4047674 | 0.68 | KMT2A (0.76) | MAPTKDM4ESMN1; SMN2KMT2ACYP1A2 | |
| SCHEMBL30506422 | 0.67 | KMT2A (0.57) | MAPTKDM4ESMN1; SMN2KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997667-A | Pyridinyl compounds of N-carbamoyl-N-thiocarbamoyl- or N-amidino-glycine or beta-alanine useful as sweetening agents | UNIVERSITE CLAUDE BERNARD (FR) | 1991-03-05 | — | — | US | disclosed |