Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | HTT | P42858 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | NPY2R | P49146 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868268 | 1.00 | MAPT (0.58) | MAPTNPSR1KDM4EGAASMN1; SMN2 | |
| SCHEMBL9868178 | 0.83 | MAPT (0.65) | MAPTNPSR1KDM4EGAASMN1; SMN2 | |
| SCHEMBL9868180 | 0.83 | MAPT (0.65) | MAPTNPSR1KDM4EGAASMN1; SMN2 | |
| SCHEMBL9868710 | 0.83 | MAPT (0.67) | MAPTNPSR1GAASMN1; SMN2HTT | |
| SCHEMBL9868712 | 0.83 | MAPT (0.67) | MAPTNPSR1GAASMN1; SMN2HTT | |
| SCHEMBL24706356 | 0.81 | MAPT (0.49) | MAPTNPSR1KDM4EGAASMN1; SMN2 | |
| SCHEMBL22130084 | 0.81 | MAPT (0.49) | MAPTNPSR1KDM4EGAASMN1; SMN2 | |
| SCHEMBL922712 | 0.79 | MAPT (0.81) | MAPTNPSR1KDM4EGAASMN1; SMN2 | |
| SCHEMBL922713 | 0.79 | MAPT (0.81) | MAPTNPSR1KDM4EGAASMN1; SMN2 | |
| SCHEMBL24599839 | 0.78 | MAPT (0.56) | MAPTNPSR1KDM4EGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412211-A1 | Cancer therapy system | THERAPEUTICAL SYSTEMS CORPORATION (US) | 1991-02-13 | — | — | EP | claimed |
| US-4935450-A | Cancer therapy system for effecting oncolysis of malignant neoplasms | THERAPEUTICAL SYSTEMS CORPORATION (US) | 1990-06-19 | — | — | US | claimed |