Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866688 | 0.91 | CCKBR (0.84) | CCKBRKCNH2 | |
| SCHEMBL14180307 | 0.90 | CCKBR (0.81) | CCKBRKCNH2 | |
| SCHEMBL5016379 | 0.88 | CCKBR (0.78) | CCKBRKCNH2 | |
| SCHEMBL8609474 | 0.85 | CCKBR (0.74) | CCKBRKCNH2 | |
| SCHEMBL14180313 | 0.85 | CCKBR (0.73) | CCKBR | |
| SCHEMBL9866668 | 0.84 | CCKBR (1.00) | CCKBRKCNH2 | |
| SCHEMBL7207460 | 0.84 | CCKBR (0.78) | CCKBR | |
| SCHEMBL2927644 | 0.84 | CCKBR (0.78) | CCKBR | |
| SCHEMBL14180310 | 0.84 | CCKBR (0.74) | CCKBR | |
| SCHEMBL7170310 | 0.83 | HDAC3 (0.76) | CCKBRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004741-A | Cholecystokinin(CCK); Treating Disorders Of The Gastrointestinal Tract, Central Nervous System And Of The Appetite Of Animals | MERCK & CO., INC. (US) | 1991-04-02 | — | — | US | disclosed |
| US-4820834-A | Benzodiazepine analogs | MERCK & CO., INC. (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0284256-A1 | Benzodiazepine analogs | MERCK & CO. INC. (US) | 1988-09-28 | — | — | EP | disclosed |