Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | VHL | P40337 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171117 | 0.81 | KMT2A (0.48) | HCAR2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL11971540 | 0.78 | HCAR2 (0.36) | HCAR2CNR2ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL28955962 | 0.78 | HCAR2 (0.36) | HCAR2CNR2ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL15193549 | 0.78 | HCAR2 (0.36) | HCAR2CNR2ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL15194040 | 0.78 | HCAR2 (0.36) | HCAR2CNR2ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL20320520 | 0.77 | HCAR2 (0.38) | HCAR2CNR2ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL15473290 | 0.77 | HCAR2 (0.38) | HCAR2CNR2ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL17809490 | 0.77 | HCAR2 (0.38) | HCAR2CNR2ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL2585201 | 0.77 | HCAR2 (0.38) | HCAR2CNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL2585198 | 0.77 | HCAR2 (0.38) | HCAR2CNR2ALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4021904-B1 | ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-01-03 | — | — | EP | disclosed |
| US-20200339589-A1 | SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES COMPOUNDS AS RET KINASE INHIBITORS | ARRAY BIOPHARMA, INC. | 2020-10-29 | — | — | US | disclosed |
| WO-2019143994-A1 | SUBSTITUTED PYRAZOLYL[4,3-C]PYRIDINECOMPOUNDS AS RET KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2019-07-25 | — | — | WO | disclosed |
| WO-2016177686-A1 | PYRIDAZINE DERIVATIVES AS RORc MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2016-11-10 | — | — | WO | disclosed |
| US-5017601-A | Anti-ulcer 5-(2-substituted ethenyl)-3(2H)-furanones | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-05-21 | — | — | US | disclosed |
| US-5010102-A | Anti-ulcer 5-(2-substituted ethenyl)-3(2H)-furanones | AMERICAN HOME PRODUCTS CORP. (US) | 1991-04-23 | — | — | US | disclosed |
| US-5001126-A | Anti-ulcer 5-(2-substituted ethenyl)-3(2H)-furanones | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-03-19 | — | — | US | disclosed |
| US-4966905-A | Anti-ulcer 5-(2-substituted ethenyl)-3-(2H)-furanones | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339589-A1 | SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES COMPOUNDS AS RET KINASE INHIBITORS | RET, ROR1, FGFR3 | HCAR2 2784/4885CNR2 4173/4885ALDH1A1 2912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.