Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27498327 | 0.87 | TSHR (0.39) | TSHRNFKB1CYP2C19GAAL3MBTL1 | |
| SCHEMBL703625 | 0.87 | TSHR (0.39) | TSHRNFKB1CYP2C19GAAL3MBTL1 | |
| Hno SCHEMBL27526743 | 0.84 | TSHR (0.40) | TSHRNFKB1CYP2C19GAAL3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL28821907 | 0.84 | TSHR (0.38) | TSHRNFKB1CYP2C19GAAL3MBTL1 | |
| Water SCHEMBL28630546 | 0.84 | TSHR (0.38) | TSHRNFKB1CYP2C19GAAL3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL27842174 | 0.81 | TSHR (0.37) | TSHRNFKB1CYP2C19GAAL3MBTL1 | |
| SCHEMBL3915903 | 0.81 | GAA (0.36) | TSHRNFKB1CYP2C19GAAL3MBTL1 | |
| SCHEMBL28404925 | 0.79 | TSHR (0.40) | TSHRNFKB1CYP2C19GAAL3MBTL1 | |
| SCHEMBL28609422 | 0.79 | TSHR (0.35) | TSHRNFKB1CYP2C19GAAL3MBTL1 | |
| SCHEMBL20731225 | 0.78 | GAA (0.35) | TSHRNFKB1CYP2C19GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7862746-B2 | Stabilization of natural composites | BASF SE. (DE) | 2011-01-04 | — | — | US | claimed |
| WO-2006087269-A1 | STABILIZATION OF NATURAL COMPOSITES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-08-24 | — | — | WO | claimed |
| US-20060183821-A1 | Stabilization of natural composites | CIBA CORPORATION | 2006-08-17 | — | — | US | claimed |
| US-7862746-B2 | Stabilization of natural composites | BASF SE. (DE) | 2011-01-04 | — | — | US | disclosed |
| WO-2006087269-A1 | STABILIZATION OF NATURAL COMPOSITES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-08-24 | — | — | WO | disclosed |
| US-20060183821-A1 | Stabilization of natural composites | CIBA CORPORATION | 2006-08-17 | — | — | US | disclosed |