Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | LIG1 | P18858 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3933331 | 0.89 | GAA (0.52) | MEN1HTTKMT2AALDH1A1HPGD | |
| SCHEMBL2187527 | 0.85 | ALDH1A1 (0.50) | MEN1HTTKMT2AALDH1A1HPGD | |
| SCHEMBL13924205 | 0.85 | FLT3 (0.55) | MEN1KMT2AALDH1A1FLT3LIG1 | |
| SCHEMBL2901176 | 0.84 | FLT3 (0.64) | MEN1KMT2AALDH1A1FLT3LIG1 | |
| SCHEMBL2374331 | 0.84 | HSP90AA1 (0.50) | HTTALDH1A1HPGDFLT3LIG1 | |
| SCHEMBL10737872 | 0.84 | GAA (0.60) | MEN1HTTKMT2AALDH1A1HPGD | |
| SCHEMBL2545851 | 0.83 | FFAR4 (0.55) | MEN1KMT2AALDH1A1FLT3LIG1 | |
| SCHEMBL7272605 | 0.83 | GAA (0.59) | MEN1KMT2AALDH1A1HPGDFLT3 | |
| SCHEMBL16055509 | 0.82 | TDP1 (0.62) | HTTKMT2AALDH1A1HPGDGAA | |
| SCHEMBL14573823 | 0.82 | FLT3 (0.46) | MEN1KMT2AALDH1A1FLT3LIG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585263-A | Phenyl substituted dihydro Cai compounds and preparation and application thereof | 苏中药业集团股份有限公司 | 2025-03-07 | — | — | CN | disclosed |
| WO-2025011008-A1 | PHARMACEUTICAL PREPARATION CONTAINING PHENYL-SUBSTITUTED DIHYDRONAPHTHYRIDINE COMPOUND, AND USE THEREOF | 苏中药业集团股份有限公司 | 2025-01-16 | — | — | WO | disclosed |
| CN-119302952-A | Pharmaceutical preparation containing phenyl substituted dihydronaphthyridine compound and application thereof | 苏中药业集团股份有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-119306715-A | Crystal of phenyl substituted dihydronaphthyridine compound and application thereof | 苏中药业集团股份有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-111116577-A | Fused tetracyclic compounds and application thereof in medicines | 广东东阳光药业有限公司 | 2020-05-08 | — | — | CN | disclosed |
| US-5006570-A | Dihydrobenzofuran- and chroman-carboxamide derivatives, processes for the preparation thereof and use thereof as neuroleptics | LABORATOIRES DELAGRANGE (FR) | 1991-04-09 | — | — | US | disclosed |