Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.45 |
| ▸ | HTR1A | P08908 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.40 |
| ▸ | MASP2 | O00187 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 3/20 | 0.33 |
| ▸ | ACE | P12821 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27571236 | 0.82 | GAA (0.61) | GAAMAPTSMYD3MTNR1AMASP2 | |
| SCHEMBL30357995 | 0.82 | SMYD3 (0.56) | GAAMAPTSMYD3MTNR1AHTR1A | |
| SCHEMBL926907 | 0.82 | SMYD3 (0.56) | GAAMAPTSMYD3MTNR1AHTR1A | |
| SCHEMBL7433964 | 0.82 | SMYD3 (0.56) | GAAMAPTSMYD3MTNR1AHTR1A | |
| SCHEMBL8567081 | 0.82 | SMYD3 (0.56) | GAAMAPTSMYD3MTNR1AHTR1A | |
| SCHEMBL9868433 | 0.82 | GAA (0.81) | GAAMAPTSMYD3MTNR1AHTR1A | |
| SCHEMBL5494843 | 0.81 | SMYD3 (0.49) | GAAMAPTSMYD3MTNR1AHTR1A | |
| Hydrochloric Acid SCHEMBL5424922 | 0.81 | SMYD3 (0.54) | GAAMAPTSMYD3MTNR1AHTR1A | |
| SCHEMBL28263579 | 0.79 | GAA (0.62) | GAAMAPTSMYD3MTNR1AF2 | |
| SCHEMBL4019694 | 0.79 | SMYD3 (0.58) | GAAMAPTSMYD3MTNR1AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017584-A | Antidepressant 2-(4,5-dihydro-1H-imidazolyl)-dihydro-1H-indoles, -1,2,3,4-tetrahydroquinolines and -1H-indoles, and methods of use thereas | STERLING DRUG INC. (US) | 1991-05-21 | — | — | US | disclosed |