Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8823266 | 0.89 | ALDH1A1 (0.59) | ALDH1A1TACR1KMT2ARAB9ACTRB1 | |
| SCHEMBL12328166 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KMT2ARAB9AGAACTRB1 | |
| SCHEMBL8823267 | 0.86 | ALDH1A1 (0.56) | ALDH1A1TACR1KMT2AMEN1HPGD | |
| SCHEMBL9335054 | 0.86 | ALDH1A1 (0.56) | ALDH1A1TACR1KMT2ARAB9ACTRB1 | |
| SCHEMBL2490603 | 0.86 | ACE (0.53) | ALDH1A1TACR1KMT2AHPGDRAB9A | |
| SCHEMBL2781038 | 0.82 | ALDH1A1 (0.51) | ALDH1A1TACR1KMT2ARAB9ACTRB1 | |
| SCHEMBL8421593 | 0.81 | TACR1 (0.55) | ALDH1A1TACR1KMT2ARAB9ACTRB1 | |
| SCHEMBL2780475 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TACR1KMT2AMEN1LMNA | |
| SCHEMBL2778101 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TACR1KMT2ARAB9ACTRB1 | |
| SCHEMBL3829691 | 0.80 | HSD17B10 (0.49) | ALDH1A1TACR1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981992-A | HYDROGENATION, RUTHENIUM COMPLEX CATALYST | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1991-01-01 | — | — | US | disclosed |