Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 6/20 | 0.67 |
| ▸ | CCR8 | P51685 | 6/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.67 |
| ▸ | CCR5 | P51681 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27836480 | 0.86 | CCR1 (0.74) | CCR1CCR8L3MBTL1CCR5KDM4E | |
| SCHEMBL2808229 | 0.83 | CCR1 (0.54) | CCR1CCR8L3MBTL1CCR5KDM4E | |
| SCHEMBL2811314 | 0.83 | MAPT (0.64) | CCR1CCR8L3MBTL1CCR5KDM4E | |
| Phenanthroline SCHEMBL21518505 | 0.82 | CCR1 (0.93) | CCR1CCR8L3MBTL1CCR5KDM4E | |
| SCHEMBL25851183 | 0.81 | CCR1 (0.57) | CCR1CCR8L3MBTL1CCR5KDM4E | |
| SCHEMBL459073 | 0.81 | KDM4E (0.61) | CCR1CCR8L3MBTL1CCR5KDM4E | |
| SCHEMBL2808095 | 0.81 | CCR1 (0.51) | CCR1CCR8L3MBTL1CCR5KDM4E | |
| SCHEMBL13892984 | 0.81 | CCR1 (0.51) | CCR1CCR8L3MBTL1CCR5KDM4E | |
| SCHEMBL21511856 | 0.81 | CCR1 (0.51) | CCR1CCR8L3MBTL1CCR5KDM4E | |
| SCHEMBL13892943 | 0.80 | CCR1 (0.69) | CCR1CCR8L3MBTL1CCR5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140011835-A1 | [1,10]-PHENANTHROLINE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE OR HAEMATOLOGICAL DISEASES | NOSCIRA, S.A. (ES) | 2014-01-09 | — | — | US | disclosed |
| US-20100240692-A1 | [1,10]-PHENANTHROLINE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE OR HAEMATOLOGICAL DISEASES | NOSCIRA, S.A. (ES) | 2010-09-23 | — | — | US | disclosed |
| US-5006660-A | Reacting a halogenbenzene with alcohol or phenol in presence od copper(or compound thereof), amine, and base | FUJI PHOTO FILM CO., LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140011835-A1 | [1,10]-PHENANTHROLINE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE OR HAEMATOLOGICAL DISEASES | HTT, PARK7, ATXN10 | CCR1 2179/4885CCR8 4099/4885L3MBTL1 2710/4885 |
| US-20100240692-A1 | [1,10]-PHENANTHROLINE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE OR HAEMATOLOGICAL DISEASES | HTT, ATXN10, PSEN1 | CCR1 2471/4885CCR8 3823/4885L3MBTL1 3762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.