Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 12/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL663121 | 0.99 | CHRM3 (0.44) | CHRM3ADRB2RAB9ANPC1PLA2G4A | |
| Iodide SCHEMBL99534 | 0.95 | NPC1 (0.46) | CHRM3ADRB2RAB9ANPC1PLA2G4A | |
| Iodide SCHEMBL101246 | 0.92 | CHRM3 (0.43) | CHRM3ADRB2 | |
| Iodide SCHEMBL100122 | 0.89 | CHRM3 (0.39) | CHRM3ADRB2 | |
| SCHEMBL661552 | 0.89 | CHRM3 (0.53) | CHRM3ADRB2 | |
| Iodide SCHEMBL101978 | 0.89 | CHRM3 (0.42) | CHRM3ADRB2 | |
| Iodide SCHEMBL99054 | 0.89 | CHRM3 (0.41) | CHRM3ADRB2RAB9ANPC1LTB4R | |
| Iodide SCHEMBL99924 | 0.88 | CHRM3 (0.39) | CHRM3ADRB2RAB9ANPC1 | |
| Iodide SCHEMBL101146 | 0.88 | CHRM3 (0.43) | CHRM3ADRB2 | |
| Iodide SCHEMBL101160 | 0.87 | CHRM3 (0.44) | CHRM3ADRB2RAB9ANPC1LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | claimed |