Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.89 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.89 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.89 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 8/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9867897 | 0.98 | CYP1A2 (0.86) | CYP1A2CYP2C9CYP2C19KDM4ECYP3A4 | |
| SCHEMBL17621161 | 0.86 | HPGD (0.74) | CYP1A2CYP2C9CYP2C19KDM4ECYP3A4 | |
| SCHEMBL10090174 | 0.84 | CYP1A2 (0.70) | CYP1A2CYP2C9CYP2C19KDM4ECYP3A4 | |
| SCHEMBL10436863 | 0.84 | CYP1A2 (0.69) | CYP1A2CYP2C9CYP2C19KDM4ECYP3A4 | |
| SCHEMBL10475269 | 0.83 | RECQL (0.71) | CYP1A2CYP2C9CYP2C19KDM4EHPGD | |
| SCHEMBL10436951 | 0.83 | CYP1A2 (0.68) | CYP1A2CYP2C9CYP2C19KDM4ECYP3A4 | |
| SCHEMBL27638118 | 0.83 | CYP3A4 (0.72) | CYP1A2CYP2C9CYP2C19KDM4ECYP3A4 | |
| SCHEMBL14759044 | 0.83 | CYP1A2 (0.67) | CYP1A2CYP2C9CYP2C19KDM4ECYP3A4 | |
| SCHEMBL6431749 | 0.83 | CYP3A4 (0.72) | CYP1A2CYP2C9CYP2C19KDM4ECYP3A4 | |
| SCHEMBL8184182 | 0.83 | RECQL (0.70) | CYP1A2CYP2C9CYP2C19KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445920-A2 | Use of ethoxy phenoxy acetic acid derivatives against diabetes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-09-11 | — | — | EP | disclosed |
| EP-0445920-A2 | Use of ethoxy phenoxy acetic acid derivatives against diabetes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-09-11 | — | — | EP | disclosed |