Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868600 | 0.84 | CYP1A2 (0.89) | CYP1A2CYP2C9CYP2C19HPGDTSHR | |
| SCHEMBL22669498 | 0.84 | MEN1 (0.67) | CYP1A2CYP2C9CYP2C19KDM4EKMT2A | |
| SCHEMBL10436951 | 0.84 | CYP1A2 (0.68) | CYP1A2CYP2C9CYP2C19HPGDTSHR | |
| Hydrochloric Acid SCHEMBL9867897 | 0.83 | CYP1A2 (0.86) | CYP1A2CYP2C9CYP2C19HPGDTSHR | |
| SCHEMBL10090423 | 0.83 | RAB9A (0.70) | CYP1A2CYP2C9CYP2C19KDM4EKMT2A | |
| SCHEMBL2554470 | 0.82 | CYP1A2 (0.67) | CYP1A2CYP2C9CYP2C19HPGDTSHR | |
| SCHEMBL11876820 | 0.82 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19KDM4EKMT2A | |
| SCHEMBL23383748 | 0.81 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19HPGDTSHR | |
| SCHEMBL27754995 | 0.81 | RAB9A (0.67) | HPGDTSHRKDM4EKMT2AMEN1 | |
| SCHEMBL8846760 | 0.80 | MEN1 (0.61) | CYP1A2CYP2C9CYP2C19KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148541-B2 | Rhodanine derivatives, a process for the preparation thereof and pharmaceutical composition containing the same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2012-04-03 | — | — | US | disclosed |
| US-20090042872-A1 | Rhodanine Derivatives, a Process for the Preparation Thereof and Pharmaceutical Composition Containing the Same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042872-A1 | Rhodanine Derivatives, a Process for the Preparation Thereof and Pharmaceutical Composition Containing the Same | PTPRR, PTPRG, PTPRS | CYP1A2 3761/4885CYP2C9 3181/4885CYP2C19 2856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.