SCHEMBL9868917

SCHEMBL9868917

Cc1cc2c(cc1C)N(C)CN2

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.39
NISCH Q9Y2I1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7922207 0.75 HDAC1 (0.37) HDAC1NISCH
SCHEMBL21991215 0.69 HDAC1 (0.36) HDAC1
SCHEMBL19957711 0.69 HDAC1 (0.49) HDAC1
SCHEMBL7027320 0.69 HDAC1 (0.36) HDAC1
SCHEMBL18306560 0.68 TNF (0.31) HDAC1
SCHEMBL20888758 0.67 GRIA2 (0.42) NISCH
SCHEMBL14156532 0.66
SCHEMBL21880578 0.66 KDM4E (0.49) HDAC1
SCHEMBL14156599 0.66 DDB1 (0.41)
SCHEMBL14156583 0.66 LMNA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5015473-A Beta-lactamase inhibitors PFIZER INC. (US) 1991-05-14 US disclosed
US-4826833-A ANTIBIOTICS PFIZER INC. (US) 1989-05-02 US disclosed