Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20098644 | 0.85 | KDM4E (0.43) | KDM4EHSD17B10TSHRNPC1RAB9A | |
| SCHEMBL13544720 | 0.84 | KDM4E (0.45) | KDM4EHSD17B10TSHRCA12CA1 | |
| SCHEMBL31325007 | 0.84 | KDM4E (0.45) | KDM4EHSD17B10TSHRCA12CA1 | |
| SCHEMBL2159957 | 0.84 | ALDH1A1 (0.43) | KDM4EHSD17B10NPC1RAB9ACYP1A2 | |
| SCHEMBL4903445 | 0.84 | TARBP2 (0.42) | KDM4EHSD17B10NPC1RAB9ACYP1A2 | |
| SCHEMBL25331182 | 0.81 | KDM4E (0.43) | KDM4EHSD17B10TSHRNPC1CASP3 | |
| SCHEMBL24212583 | 0.81 | KDM4E (0.40) | KDM4EHSD17B10NPC1CYP1A2ALDH1A1 | |
| SCHEMBL15058465 | 0.80 | NPSR1 (0.42) | KDM4EHSD17B10TSHRCA12CA1 | |
| SCHEMBL30830184 | 0.80 | CSNK1D (0.45) | KDM4EHSD17B10TSHRCA12CA1 | |
| SCHEMBL4598550 | 0.80 | NPC1 (0.51) | KDM4EHSD17B10TSHRNPC1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997947-A | Forming 6-substituted pyridine-2,3-dicarboxylic esters followed by reacting with aminoalkanecarboxylic acid amide; herbicides, plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |