Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.54 |
| ▸ | GBA1 | P04062 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GBA2 | Q9HCG7 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368683 | 0.98 | BRD4 (0.56) | BRD4GBA1L3MBTL1ALDH1A1PRKCD | |
| SCHEMBL11623610 | 0.93 | BRD4 (0.58) | BRD4GBA1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL9368747 | 0.82 | GBA1 (0.42) | BRD4GBA1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL8076306 | 0.76 | POLB (0.56) | GBA1L3MBTL1ALDH1A1MEN1CYP2C19 | |
| SCHEMBL15082405 | 0.76 | POLB (0.56) | GBA1L3MBTL1ALDH1A1MEN1CYP2C19 | |
| SCHEMBL8084202 | 0.76 | POLB (0.56) | GBA1L3MBTL1ALDH1A1MEN1CYP2C19 | |
| SCHEMBL2890516 | 0.76 | POLB (0.56) | GBA1L3MBTL1ALDH1A1MEN1CYP2C19 | |
| SCHEMBL119623 | 0.76 | POLB (0.56) | GBA1L3MBTL1ALDH1A1MEN1CYP2C19 | |
| SCHEMBL8084223 | 0.76 | POLB (0.56) | GBA1L3MBTL1ALDH1A1MEN1CYP2C19 | |
| SCHEMBL14477954 | 0.76 | POLB (0.56) | GBA1L3MBTL1ALDH1A1MEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985521-A | COPOLYMERS, COMPLEXES WITH WATER INSOLUBLE MOLECULES | GAF CHEMICALS CORPORATION (US) | 1991-01-15 | — | — | US | disclosed |
| US-4946967-A | CHEMICAL INTERMEDIATES FOR HIGH MOLECULAR WEIGHT ACYCLIC ESTER OR AMIDE | GAF CHEMICALS CORPORATION (US) | 1990-08-07 | — | — | US | disclosed |