SCHEMBL986928

SCHEMBL986928

C=CC(c1ccccc1)N1CCN(C)CC1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 5/20 0.59
CHRM2 P08172 5/20 0.59
CHRM1 P11229 5/20 0.59
ADRA2A P08913 4/20 0.59
DRD1 P21728 4/20 0.59
DRD3 P35462 4/20 0.59
SLC6A3 Q01959 4/20 0.59
KCNH2 Q12809 4/20 0.59
OPRM1 P35372 3/20 0.59
CHRM4 P08173 1/20 0.59
CHRM5 P08912 1/20 0.59
ADORA3 P0DMS8 1/20 0.59
CHRM3 P20309 1/20 0.59
ADRA1D P25100 1/20 0.59
HTR2A P28223 1/20 0.59
HTR2C P28335 1/20 0.59
HRH1 P35367 1/20 0.59
HTR2B P41595 1/20 0.59
MC4R P32245 4/20 0.58
HTR1A P08908 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2579537 0.91 CYP2D6 (0.48) CYP2D6CHRM2CHRM1ADRA2ADRD1
SCHEMBL11645727 0.84 CHRM2 (0.56) CYP2D6CHRM2CHRM1ADRA2ADRD1
SCHEMBL27628069 0.84 CYP2D6 (0.61) CYP2D6CHRM2CHRM1ADRA2ADRD1
SCHEMBL29078136 0.84 CHRM2 (0.56) CYP2D6CHRM2CHRM1ADRA2ADRD1
SCHEMBL3294321 0.83 CYP2D6 (0.55) CYP2D6CHRM2CHRM1ADRA2ADRD1
SCHEMBL12066465 0.82 CHRM1 (0.59) CYP2D6CHRM2CHRM1ADRA2ADRD1
SCHEMBL13258519 0.82 CHRM1 (0.59) CYP2D6CHRM2CHRM1ADRA2ADRD1
SCHEMBL6837651 0.81 CYP1A2 (0.57) CYP2D6KCNH2TSHRCYP2C19ALDH1A1
SCHEMBL6838012 0.81 CYP1A2 (0.57) CYP2D6KCNH2TSHRCYP2C19ALDH1A1
SCHEMBL30518149 0.81 CYP1A2 (0.57) CYP2D6KCNH2TSHRCYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2513091-B1 HEPATITIS C VIRUS INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2017-04-12 EP disclosed
EP-1866166-B1 INK SET FOR INK JET RECORDING, INK FOR INK JET RECORDING, AND INK JET IMAGE RECORDING METHOD FUJIFILM CORP (JP) 2012-10-24 EP disclosed
US-7866807-B2 Ink set for ink jet recording, ink for ink jet recording, and ink jet image recording method FUJIFILM CORPORATION (JP) 2011-01-11 US disclosed
US-7857407-B2 Image forming apparatus FUJIFILM CORPORATION (JP) 2010-12-28 US disclosed
US-7753462-B2 Image forming apparatus FUJIFILM CORPORATION (JP) 2010-07-13 US disclosed
US-7712887-B2 Image forming apparatus FUJIFILM CORPORATION (JP) 2010-05-11 US disclosed
US-7651213-B2 Image forming apparatus and image forming method FUJIFILM CORPORATION (JP) 2010-01-26 US disclosed
US-20090081367-A1 Ink set for ink jet recording, ink for ink jet recording, and ink jet image recording method FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
EP-1866166-A1 INK SET FOR INK JET RECORDING, INK FOR INK JET RECORDING, AND INK JET IMAGE RECORDING METHOD FUJIFILM CORPORATION (JP) 2007-12-19 EP disclosed
US-20070046715-A1 Image forming apparatus FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070046719-A1 Image forming apparatus FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070024686-A1 Image forming apparatus FUJI PHOTO FILM CO., LTD. 2007-02-01 US disclosed
US-20070024684-A1 Image forming apparatus and image forming method FUJI PHOTO FILM CO., LTD. 2007-02-01 US disclosed
WO-2006104281-A1 INK SET FOR INK JET RECORDING, INK FOR INK JET RECORDING, AND INK JET IMAGE RECORDING METHOD FUJIFILM CORPORATION (JP) 2006-10-05 WO disclosed