Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TOP2A | P11388 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9870957 | 0.99 | TOP1 (0.59) | TOP1KDM4EHPGDHSD17B10ADRA2B | |
| SCHEMBL9869653 | 0.90 | PIM1 (0.51) | TOP1KDM4EHPGDHSD17B10ADRA2B | |
| SCHEMBL10584919 | 0.90 | TOP1 (0.49) | TOP1KDM4EHPGDHSD17B10ADRA2B | |
| SCHEMBL9870287 | 0.87 | KDM4E (0.67) | TOP1KDM4EHPGDHSD17B10ADRA2B | |
| Hydrochloric Acid SCHEMBL9870743 | 0.86 | KDM4E (0.66) | TOP1KDM4EHPGDHSD17B10ADRA2B | |
| SCHEMBL9869795 | 0.85 | KDM4E (0.58) | TOP1KDM4EHPGDHSD17B10ADRA2B | |
| SCHEMBL10669422 | 0.85 | KDM4E (0.58) | TOP1KDM4EHPGDHSD17B10ADRA2B | |
| SCHEMBL10664056 | 0.83 | KDM4E (0.56) | TOP1KDM4EHPGDHSD17B10ADRA2B | |
| SCHEMBL10672942 | 0.83 | KDM4E (0.56) | TOP1KDM4EHPGDHSD17B10ADRA2B | |
| Hydrochloric Acid SCHEMBL10669877 | 0.82 | KDM4E (0.56) | TOP1KDM4EHPGDHSD17B10ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981854-A | BACTERICIDES, ANIMAL GROWTH REGUALTORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-01 | — | — | US | claimed |
| US-4980353-A | BACTERICIDES, ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | claimed |
| EP-0201829-A1 | 1-Aryl-4-quinolone-3-carboxylic acids | BAYER AG (DE) | 1986-11-20 | — | — | EP | claimed |
| EP-0318468-A1 | 2,4-Dichloro-5-fluoro-3-nitrobenzoic acid and its derivatives | BAYER AG (DE) | 1989-05-31 | — | — | EP | disclosed |
| EP-0201829-A1 | 1-Aryl-4-quinolone-3-carboxylic acids | BAYER AG (DE) | 1986-11-20 | — | — | EP | disclosed |