Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.51 |
| ▸ | TOP1 | P11387 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 5/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10914802 | 0.90 | PIM1 (0.41) | PIM1TOP1HPGDHSD17B10KDM4E | |
| SCHEMBL9869314 | 0.90 | TOP1 (0.60) | PIM1TOP1HPGDHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL9870957 | 0.89 | TOP1 (0.59) | PIM1TOP1HPGDHSD17B10KDM4E | |
| SCHEMBL9870372 | 0.88 | HPGD (0.61) | TOP1HPGDHSD17B10KDM4EALDH1A1 | |
| SCHEMBL10913380 | 0.82 | KDM4E (0.55) | PIM1TOP1HPGDHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL9870882 | 0.81 | KDM4E (0.54) | PIM1TOP1HPGDHSD17B10KDM4E | |
| SCHEMBL10914433 | 0.81 | HPGD (0.55) | PIM1TOP1HPGDHSD17B10KDM4E | |
| SCHEMBL10584919 | 0.80 | TOP1 (0.49) | PIM1TOP1HPGDHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL9870344 | 0.80 | HPGD (0.54) | PIM1TOP1HPGDHSD17B10KDM4E | |
| SCHEMBL6213952 | 0.78 | PIM1 (0.58) | PIM1TOP1HPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981854-A | BACTERICIDES, ANIMAL GROWTH REGUALTORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-01 | — | — | US | claimed |
| US-4980353-A | BACTERICIDES, ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | claimed |
| EP-0201829-A1 | 1-Aryl-4-quinolone-3-carboxylic acids | BAYER AG (DE) | 1986-11-20 | — | — | EP | claimed |
| US-4981854-A | BACTERICIDES, ANIMAL GROWTH REGUALTORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-01 | — | — | US | disclosed |
| US-4980353-A | BACTERICIDES, ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | disclosed |
| EP-0201829-A1 | 1-Aryl-4-quinolone-3-carboxylic acids | BAYER AG (DE) | 1986-11-20 | — | — | EP | disclosed |