Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11464623 | 0.78 | KDM4E (0.62) | KDM4DKDM4EALDH1A1ARHPGD | |
| SCHEMBL9468727 | 0.77 | KDM4E (0.65) | KDM4DKDM4EALDH1A1HPGDCLK4 | |
| SCHEMBL3160795 | 0.73 | KDM4D (0.52) | KDM4DKDM4EALDH1A1HPGDCLK4 | |
| SCHEMBL14014371 | 0.71 | KDM4E (0.59) | KDM4DKDM4EALDH1A1HPGDCLK4 | |
| SCHEMBL10334307 | 0.71 | KDM4E (0.61) | KDM4DKDM4EALDH1A1HPGDCLK4 | |
| SCHEMBL10554497 | 0.70 | KDM4E (0.47) | KDM4DKDM4EALDH1A1HPGDCLK4 | |
| SCHEMBL29071791 | 0.69 | KDM4E (0.67) | KDM4DKDM4EALDH1A1HPGDCLK4 | |
| SCHEMBL4706821 | 0.66 | KDM4E (0.52) | KDM4DKDM4EALDH1A1HPGDCLK4 | |
| SCHEMBL4708050 | 0.66 | KDM4E (0.52) | KDM4DKDM4EALDH1A1HPGDCLK4 | |
| SCHEMBL14013969 | 0.66 | KDM4D (0.46) | KDM4DKDM4EALDH1A1HPGDCLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013737-A | Hypotensive, anxiolytic, cognitive disorders | AMERICAN CYANAMID COMPANY (US) | 1991-05-07 | — | — | US | disclosed |