Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.52 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.52 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9383178 | 0.97 | KCNH2 (0.53) | KCNH2SLC22A2ADRB1SLC6A4SLC47A2 | |
| Oxalic Acid SCHEMBL9387858 | 0.95 | KCNH2 (0.51) | KCNH2SLC22A2ADRB1SLC6A4SLC47A2 | |
| SCHEMBL9385340 | 0.90 | KCNH2 (0.60) | KCNH2SLC22A2ADRB1SLC6A4SLC47A2 | |
| SCHEMBL9385760 | 0.90 | KCNH2 (0.52) | KCNH2SLC22A2ADRB1SLC6A4SLC47A2 | |
| SCHEMBL9389045 | 0.87 | KCNH2 (0.61) | KCNH2SLC22A2ADRB1SLC6A4SLC47A2 | |
| SCHEMBL9389527 | 0.87 | KCNH2 (0.50) | KCNH2SLC22A2ADRB1SLC6A4SLC47A2 | |
| SCHEMBL9383236 | 0.86 | SLC22A2 (0.51) | KCNH2SLC22A2ADRB1SLC6A4SLC47A2 | |
| SCHEMBL9385003 | 0.86 | PKM (0.52) | KCNH2SLC22A2ADRB1SLC6A4SLC47A2 | |
| Hydrochloric Acid SCHEMBL9384571 | 0.85 | SLC22A2 (0.50) | KCNH2SLC22A2ADRB1SLC6A4SLC47A2 | |
| SCHEMBL9386225 | 0.85 | KCNH2 (0.55) | KCNH2SLC22A2ADRB1SLC6A4SLC47A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0369627-A2 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | disclosed |