Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
| ▸ | PIM1 | P11309 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | TOP1 | P11387 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 2/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869850 | 0.90 | ALDH1A1 (0.65) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL6213800 | 0.90 | ALDH1A1 (0.67) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL9869480 | 0.89 | ALDH1A1 (0.72) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL10372132 | 0.89 | ALDH1A1 (0.65) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL6214789 | 0.88 | KDM4E (0.65) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL9868878 | 0.88 | ALDH1A1 (0.64) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL10912940 | 0.85 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL9048080 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL10635656 | 0.84 | ALDH1A1 (0.61) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL9871156 | 0.84 | HTT (0.62) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981854-A | BACTERICIDES, ANIMAL GROWTH REGUALTORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-01 | — | — | US | disclosed |
| US-4980353-A | BACTERICIDES, ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | disclosed |
| EP-0201829-A1 | 1-Aryl-4-quinolone-3-carboxylic acids | BAYER AG (DE) | 1986-11-20 | — | — | EP | disclosed |