Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 8/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869612 | 1.00 | ATM (0.47) | ATMHCAR2KEAP1NFE2L2TDP1 | |
| SCHEMBL29089346 | 0.87 | ATM (0.40) | ATMHCAR2TDP1LMNAALDH1A1 | |
| SCHEMBL3368716 | 0.84 | TSHR (0.50) | ATMTDP1LMNAALDH1A1CYP3A4 | |
| SCHEMBL10535335 | 0.81 | ATM (0.48) | ATMHCAR2KEAP1NFE2L2TDP1 | |
| SCHEMBL10535296 | 0.81 | ATM (0.48) | ATMHCAR2KEAP1NFE2L2TDP1 | |
| SCHEMBL12330817 | 0.80 | ALDH1A1 (0.36) | TDP1ALDH1A1TSHR | |
| SCHEMBL29546719 | 0.80 | ALDH1A1 (0.36) | TDP1ALDH1A1TSHR | |
| SCHEMBL9709226 | 0.80 | ATM (0.52) | ATMHCAR2KEAP1NFE2L2MAPT | |
| SCHEMBL23373259 | 0.80 | ATM (0.48) | ATMHCAR2MAPTRAB9ANPSR1 | |
| Acetic Acid SCHEMBL28064195 | 0.80 | TSHR (0.46) | HCAR2TDP1LMNAALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253011-B1 | COPOLYMERS OF BENZOTRIAZOL MONOMERS WITH MALEIC OR FUMARIC ACID DERIVATIVES AND POLYMERIC MATERIAL COMPOSITIONS | MORISAWA & CO., LTD. (JP) | 1991-03-20 | — | — | EP | disclosed |
| EP-0253011-A1 | Copolymers of benzotriazol monomers with maleic or fumaric acid derivatives and polymeric material compositions | MORISAWA & CO., LTD. (JP) | 1988-01-20 | — | — | EP | disclosed |