Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 8/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500198 | 1.00 | PTGER2 (0.46) | PTGER2CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL9500518 | 1.00 | PTGER2 (0.46) | PTGER2CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL9498692 | 1.00 | PTGER2 (0.46) | PTGER2CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL9499399 | 1.00 | PTGER2 (0.46) | PTGER2CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL9870071 | 0.99 | CYP2C9 (0.46) | PTGER2CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL9500501 | 0.94 | CYP2C9 (0.47) | PTGER2CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL13153844 | 0.89 | PTGER2 (0.46) | PTGER2CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL9869753 | 0.88 | CYP2C9 (0.56) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL11208419 | 0.85 | SPHK1 (0.54) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL11196171 | 0.85 | SPHK1 (0.54) | CYP2C9ALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |