Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870071 | 0.96 | CYP2C9 (0.46) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9869683 | 0.94 | PTGER2 (0.46) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9498692 | 0.94 | PTGER2 (0.46) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9499399 | 0.94 | PTGER2 (0.46) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9500518 | 0.94 | PTGER2 (0.46) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9500198 | 0.94 | PTGER2 (0.46) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9869753 | 0.91 | CYP2C9 (0.56) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL13153844 | 0.86 | PTGER2 (0.46) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9500840 | 0.84 | ALDH1A1 (0.50) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL11185308 | 0.84 | CYP2C9 (0.56) | CYP2C9ALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |