Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28410249 | 0.96 | POLB (0.51) | POLBMAPTALDH1A1HTR1BKEAP1 | |
| SCHEMBL28806667 | 0.85 | PPARG (0.45) | POLBMAPTALDH1A1ATMMEN1 | |
| SCHEMBL2253707 | 0.83 | PPARG (0.44) | POLBMAPTALDH1A1ATMMEN1 | |
| SCHEMBL28419898 | 0.80 | PPARG (0.44) | POLBMAPTALDH1A1ATMMEN1 | |
| SCHEMBL27794544 | 0.79 | POLB (0.49) | POLBMAPTALDH1A1HTR1BKEAP1 | |
| SCHEMBL31498232 | 0.77 | POLB (0.56) | POLBMAPTALDH1A1HTR1BKEAP1 | |
| SCHEMBL473084 | 0.77 | POLB (0.56) | POLBMAPTALDH1A1HTR1BKEAP1 | |
| SCHEMBL1837507 | 0.75 | POLB (0.57) | POLBMAPTALDH1A1HTR1BTRPA1 | |
| SCHEMBL21551689 | 0.74 | POLB (0.53) | POLBMAPTALDH1A1HTR1BKEAP1 | |
| SCHEMBL29004182 | 0.74 | PPARG (0.40) | POLBMAPTALDH1A1ATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055211-A | Lubricating oil containing a mixed ligand metal complex and a metal thiophosphate | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1991-10-08 | — | — | US | disclosed |