Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31498232 | 1.00 | POLB (0.56) | POLBMAPTMEN1KMT2AACHE | |
| SCHEMBL21551689 | 0.85 | POLB (0.53) | POLBMAPTMEN1KMT2AACHE | |
| SCHEMBL28823408 | 0.84 | MEN1 (0.45) | POLBMAPTMEN1KMT2AACHE | |
| SCHEMBL29525400 | 0.83 | POLB (0.59) | POLBMAPTMEN1KMT2AACHE | |
| SCHEMBL473212 | 0.83 | ATM (0.47) | MAPTMEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL6537087 | 0.83 | POLB (0.59) | POLBMAPTMEN1KMT2AACHE | |
| SCHEMBL1803105 | 0.83 | POLB (0.59) | POLBMAPTMEN1KMT2AACHE | |
| SCHEMBL29728559 | 0.82 | PTPN1 (0.49) | POLBMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL1837507 | 0.82 | POLB (0.57) | POLBMAPTMEN1KMT2AACHE | |
| SCHEMBL742810 | 0.82 | ACHE (0.62) | POLBMAPTMEN1KMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190031627-A1 | A KIND OF ISOTHIAZOLE OXIME ETHER-CONTAINING STROBILURIN DERIVATIVES AND ITS PREPARATION METHODS AND APPLICATION | NANKAI UNIVERSITY (CN) | 2019-01-31 | — | — | US | claimed |
| CN-104359990-B | A kind of analyzing detecting method of (S) or (R)-4-chloro-3-hydroxyl butyronitrile | 浙江海正药业股份有限公司 | 2016-09-07 | — | — | CN | claimed |
| CN-104359990-A | Analysis and detection method of (S) or (R)-4-chlorine-3-hydroxyl butyronitrile | ZHEJIANG HISUN PHARM CO LTD | 2015-02-18 | — | — | CN | claimed |
| CN-103604894-A | Method for separating and determining bortezomib chiral isomers through high-performance liquid chromatography | SHENZHEN MAIN LUCK PHARMACEUTICALS INC | 2014-02-26 | — | — | CN | claimed |
| CN-102297905-A | HPLC (High Performance Liquid Chromatography) method for utilizing chiral column to separate, identify and prepare monomer matter from cucurbitacin mixture | — | 2011-12-28 | — | — | CN | claimed |
| EP-3795561-B1 | METHOD FOR PRODUCING CARBAMATE AND METHOD FOR PRODUCING ISOCYANATE | ASAHI CHEMICAL IND (JP) | 2024-11-06 | — | — | EP | disclosed |
| EP-4446310-A1 | METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND | Asahi Kasei Kabushiki Kaisha (JP) | 2024-10-16 | — | — | EP | disclosed |
| CN-118382612-A | Method for producing blocked isocyanate compound and method for producing isocyanate compound | 旭化成株式会社 | 2024-07-23 | — | — | CN | disclosed |
| CN-118215651-A | Method for producing isocyanate compound, method for producing urethane compound, method for recovering amine compound, and isocyanate composition | 旭化成株式会社 | 2024-06-18 | — | — | CN | disclosed |
| US-11716992-B2 | 5A5B6C tricyclic spirolactone derivative, preparation method therefor and use thereof | NANKAI UNIVERSITY (CN) | 2023-08-08 | — | — | US | disclosed |
| WO-2023080257-A1 | METHOD FOR PRODUCING ISOCYANATE COMPOUNDS, METHOD FOR PRODUCING CARBAMATE COMPOUNDS, METHOD FOR RECOVERING AMINE COMPOUNDS, AND ISOCYANATE COMPOSITION | 旭化成株式会社 | 2023-05-11 | — | — | WO | disclosed |
| CN-112020493-B | Method for producing urethane and method for producing isocyanate | 旭化成株式会社 | 2023-04-21 | — | — | CN | disclosed |
| WO-1999058530-A1 | WATER SOLUBLE AZOLES AS BROAD-SPECTRUM ANTIFUNGALS | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-11-18 | — | — | WO | disclosed |
| EP-0957101-A1 | Water soluble azoles as broad-spectrum antifungals | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-11-17 | — | — | EP | disclosed |
| WO-1999047228-A1 | IMPROVED METHOD FOR ENRICHING OPTICAL ISOMERS BY MEANS OF SIMULATED MOBILE BED | NOVASEP S.A. (FR) | 1999-09-23 | — | — | WO | disclosed |
| WO-1999002496-A1 | (+)-NORCISAPRIDE USEFUL FOR 5-HT3 AND 5-HT4 MEDIATED DISORDERS | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-01-21 | — | — | WO | disclosed |
| WO-1998034934-A1 | AMINO ACID ESTER CONTAINING AZOLE ANTIFUNGALS | JANSSEN PHARMACEUTICA N.V. (BE) | 1998-08-13 | — | — | WO | disclosed |
| CN-1126628-A | Simulated moving bed chromatographic separation process | DAICEL CHEM (JP) | 1996-07-17 | — | — | CN | disclosed |
| US-4497887-A | Thermal development type diazo copying material with hydrophobic resin encapsulated coupler particle | Ricoh Compay, Ltd. (JP) | 1985-02-05 | — | — | US | disclosed |
| US-4226883-A | Carbamate derivatives and method for manufacture thereof | YAMAMOTO IZURU | 1980-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11716992-B2 | 5A5B6C tricyclic spirolactone derivative, preparation method therefor and use thereof | CYP51A1, CYP4B1, CYP7B1 | POLB 3740/4885MAPT 4293/4885MEN1 2183/4885 |
| US-20190031627-A1 | A KIND OF ISOTHIAZOLE OXIME ETHER-CONTAINING STROBILURIN DERIVATIVES AND ITS PREPARATION METHODS AND APPLICATION | STS, CDV3, SALL4 | POLB 4351/4885MAPT 2178/4885MEN1 4012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.