SCHEMBL9869731

SCHEMBL9869731

O=C1c2cccc3c(NCCO)ccc(c23)C(=O)N1CCO

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK3 O43781 1/20 0.69
RPS6KB1 P23443 1/20 0.69
EPHA2 P29317 1/20 0.69
FLT4 P35916 1/20 0.69
CSNK2A1 P68400 1/20 0.69
MEN1 O00255 5/20 0.65
KMT2A Q03164 5/20 0.65
HTT P42858 4/20 0.65
MAPT P10636 3/20 0.65
USP2 O75604 2/20 0.65
L3MBTL1 Q9Y468 2/20 0.65
RGS12 O14924 2/20 0.65
POLB P06746 1/20 0.65
MAPK1 P28482 1/20 0.65
ATM Q13315 1/20 0.65
NPSR1 Q6W5P4 1/20 0.65
TLR9 Q9NR96 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
HDAC1 Q13547 4/20 0.58
HDAC6 Q9UBN7 4/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12463131 0.91 DYRK3 (0.65) DYRK3RPS6KB1EPHA2FLT4CSNK2A1
SCHEMBL1580657 0.89 KMT2A (0.84) DYRK3RPS6KB1EPHA2FLT4CSNK2A1
SCHEMBL12660545 0.89 DYRK3 (0.80) DYRK3RPS6KB1EPHA2FLT4CSNK2A1
SCHEMBL1505152 0.87 MEN1 (0.73) DYRK3RPS6KB1EPHA2FLT4CSNK2A1
SCHEMBL30360198 0.87 MEN1 (0.73) DYRK3RPS6KB1EPHA2FLT4CSNK2A1
SCHEMBL19600231 0.85 MEN1 (0.69) DYRK3RPS6KB1EPHA2FLT4CSNK2A1
SCHEMBL1505144 0.85 MEN1 (0.70) DYRK3RPS6KB1EPHA2FLT4CSNK2A1
SCHEMBL1505234 0.85 MEN1 (0.70) DYRK3RPS6KB1EPHA2FLT4CSNK2A1
SCHEMBL11932615 0.83 DYRK3 (0.59) DYRK3RPS6KB1EPHA2FLT4CSNK2A1
SCHEMBL19718354 0.83 KMT2A (0.86) DYRK3RPS6KB1EPHA2FLT4CSNK2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2480610-B1 MIGRATION-FREE COLOURED COPOLYCONDENSATES FOR COLOURING POLYMERS BASF SE (DE) 2017-11-29 EP disclosed
US-20120172529-A1 MIGRATION-FREE COLOURED COPOLYCONDENSATES FOR COLOURING POLYMERS BASF SE (DE) 2012-07-05 US disclosed
US-20120172529-A1 MIGRATION-FREE COLOURED COPOLYCONDENSATES FOR COLOURING POLYMERS BASF SE (DE) 2012-07-05 US disclosed
WO-2011036075-A1 MIGRATION-FREE COLOURED COPOLYCONDENSATES FOR COLOURING POLYMERS BASF SE (DE) 2011-03-31 WO disclosed
CN-1152941-C Electroluminescent block polymers containing more function groups and its application 华东理工大学 2004-06-09 CN disclosed
CN-1266877-A Electroluminescent block polymers containing more function groups and its application HUADONG SCIENCE & ENGINEERING (CN) 2000-09-20 CN disclosed
US-5034526-A Photoinitiators for duplication, copies and images MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-07-23 US disclosed
US-4049376-A FIBER-REACTIVE DYE OF NITROGEN-CONTAINING POLYCYCLIC RING PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-09-20 US disclosed