SCHEMBL19600231

SCHEMBL19600231

CNc1ccc2c3c(cccc13)C(=O)N(CCO)C2=O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.69
KMT2A Q03164 6/20 0.69
USP2 O75604 3/20 0.69
KEAP1 Q14145 3/20 0.69
NFE2L2 Q16236 3/20 0.69
DYRK3 O43781 1/20 0.58
RPS6KB1 P23443 1/20 0.58
EPHA2 P29317 1/20 0.58
FLT4 P35916 1/20 0.58
CSNK2A1 P68400 1/20 0.58
HEXA P06865 1/20 0.57
HEXB P07686 1/20 0.57
MAPT P10636 4/20 0.57
NPC1 O15118 2/20 0.57
RAB9A P51151 2/20 0.57
AVPR1A P37288 1/20 0.57
TLR9 Q9NR96 2/20 0.56
HTT P42858 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
POLB P06746 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28332982 0.86 HEXA (0.57) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL9869731 0.85 DYRK3 (0.69) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL19342781 0.85 KMT2A (0.77) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL11921693 0.80 MEN1 (0.77) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL11256119 0.80 MEN1 (0.65) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL27812935 0.79 DYRK3 (0.76) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL29493708 0.78 CYP1B1 (0.68) MEN1KMT2AHEXAHEXBMAPT
SCHEMBL7735555 0.78 KDM4E (0.68) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL30353799 0.78 CYP1B1 (0.68) MEN1KMT2AHEXAHEXBMAPT
SCHEMBL10261817 0.78 CYP1B1 (0.68) MEN1KMT2AHEXAHEXBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170327509-A1 TWO-PHOTON ABSORBING FLUOROPHORES AND METHOD FOR CELLULAR IMAGING USING THE SAME POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2017-11-16 US disclosed
US-20170327509-A1 TWO-PHOTON ABSORBING FLUOROPHORES AND METHOD FOR CELLULAR IMAGING USING THE SAME POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2017-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170327509-A1 TWO-PHOTON ABSORBING FLUOROPHORES AND METHOD FOR CELLULAR IMAGING USING THE SAME ACE2, DNPEP, ACE MEN1 2490/4885KMT2A 3672/4885USP2 2688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.