Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 1.00 |
| ▸ | TBXA2R | P21731 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | PKM | P14618 | 2/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | FABP4 | P15090 | 3/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567621 | 1.00 | ALDH1A1 (1.00) | ALDH1A1TBXA2RLMNAPKMKDM4E | |
| SCHEMBL599970 | 1.00 | ALDH1A1 (1.00) | ALDH1A1TBXA2RLMNAPKMKDM4E | |
| SCHEMBL4595308 | 1.00 | ALDH1A1 (1.00) | ALDH1A1TBXA2RLMNAPKMKDM4E | |
| SCHEMBL31522350 | 1.00 | ALDH1A1 (1.00) | ALDH1A1TBXA2RLMNAPKMKDM4E | |
| SCHEMBL9869749 | 1.00 | ALDH1A1 (1.00) | ALDH1A1TBXA2RLMNAPKMKDM4E | |
| SCHEMBL9567728 | 1.00 | ALDH1A1 (1.00) | ALDH1A1TBXA2RLMNAPKMKDM4E | |
| SCHEMBL3383427 | 0.98 | ALDH1A1 (0.97) | ALDH1A1TBXA2RLMNAPKMKDM4E | |
| SCHEMBL911198 | 0.93 | ALDH1A1 (0.87) | ALDH1A1TBXA2RLMNAPKMKDM4E | |
| SCHEMBL2008191 | 0.89 | ALDH1A1 (0.80) | ALDH1A1TBXA2RLMNAPKMKDM4E | |
| SCHEMBL3171207 | 0.89 | ALDH1A1 (0.79) | ALDH1A1TBXA2RLMNAPKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997847-A | Thromboxane A2 antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (DE) | 1991-03-05 | — | — | US | disclosed |
| EP-0304271-A2 | Omega-arylsulphonamidoalkanoic acids for treatment of thromboxane medited diseases | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-02-22 | — | — | EP | disclosed |