Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | MPO | P05164 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.71 |
| ▸ | ECE1 | P42892 | 7/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11855463 | 1.00 | ACE (0.72) | ACEKDM4EMEN1LMNAMPO | |
| SCHEMBL3359705 | 1.00 | ACE (0.72) | ACEKDM4EMEN1LMNAMPO | |
| SCHEMBL14595067 | 1.00 | ACE (0.72) | ACEKDM4EMEN1LMNAMPO | |
| SCHEMBL9596897 | 1.00 | ACE (0.72) | ACEKDM4EMEN1LMNAMPO | |
| SCHEMBL9596908 | 1.00 | ACE (0.72) | ACEKDM4EMEN1LMNAMPO | |
| SCHEMBL29701966 | 1.00 | ACE (0.72) | ACEKDM4EMEN1LMNAMPO | |
| SCHEMBL5612810 | 1.00 | ACE (0.72) | ACEKDM4EMEN1LMNAMPO | |
| SCHEMBL5583839 | 1.00 | ACE (0.72) | ACEKDM4EMEN1LMNAMPO | |
| SCHEMBL30862445 | 0.98 | ACE (0.69) | ACEKDM4EMEN1LMNAMPO | |
| SCHEMBL9868128 | 0.98 | ACE (0.69) | ACEKDM4EMEN1LMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101747411-B | Aminoacyl tryptophyl tryptophan tripeptide benzyl ester as well as preparation method and application thereof | UNIV BEIJING | 2012-07-25 | — | — | CN | claimed |
| CN-101747411-A | Aminoacyl tryptophyl tryptophan tripeptide benzyl ester as well as preparation method and application thereof | UNIV BEIJING | 2010-06-23 | — | — | CN | claimed |
| US-20230225332-A1 | COMPOSITIONS COMPRISING AROMATIC DIPEPTIDES-BASED STRUCTURES ENCAPSULATING AN ESTERASE AND USES THEREOF | MIGAL GALILEE RES INSTITUTE LTD (IL) | 2023-07-20 | — | — | US | disclosed |
| EP-4167745-A1 | COMPOSITIONS COMPRISING AROMATIC DIPEPTIDES-BASED STRUCTURES ENCAPSULATING AN ESTERASE AND USES THEREOF | Migal Galilee Research Institute Ltd. (IL) | 2023-04-26 | — | — | EP | disclosed |
| CN-102477068-B | Amino acid derivative for preparing thrombus dissolving medicament, and preparation method and application thereof | UNIV CAPITAL MEDICAL SCIENCES | 2013-07-24 | — | — | CN | disclosed |
| CN-101747411-B | Aminoacyl tryptophyl tryptophan tripeptide benzyl ester as well as preparation method and application thereof | UNIV BEIJING | 2012-07-25 | — | — | CN | disclosed |
| CN-101747411-B | Aminoacyl tryptophyl tryptophan tripeptide benzyl ester as well as preparation method and application thereof | UNIV BEIJING | 2012-07-25 | — | — | CN | disclosed |
| CN-101747411-B | Aminoacyl tryptophyl tryptophan tripeptide benzyl ester as well as preparation method and application thereof | UNIV BEIJING | 2012-07-25 | — | — | CN | disclosed |
| CN-102477068-A | Amino acid derivative for preparing thrombus dissolving medicament, and preparation method and application thereof | UNIV CAPITAL MEDICAL | 2012-05-30 | — | — | CN | disclosed |
| CN-101747411-A | Aminoacyl tryptophyl tryptophan tripeptide benzyl ester as well as preparation method and application thereof | UNIV BEIJING | 2010-06-23 | — | — | CN | disclosed |
| CN-101747411-A | Aminoacyl tryptophyl tryptophan tripeptide benzyl ester as well as preparation method and application thereof | UNIV BEIJING | 2010-06-23 | — | — | CN | disclosed |
| CN-101747411-A | Aminoacyl tryptophyl tryptophan tripeptide benzyl ester as well as preparation method and application thereof | UNIV BEIJING | 2010-06-23 | — | — | CN | disclosed |
| US-7405238-B2 | Pharmacological inducement of the fed mode for enhanced drug administration to the stomach | DEPOMED INC. (US) | 2008-07-29 | — | — | US | disclosed |
| US-20070015813-A1 | Treatment of protein folding disorders | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2007-01-18 | — | — | US | disclosed |
| US-20070015813-A1 | Treatment of protein folding disorders | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2007-01-18 | — | — | US | disclosed |
| EP-0234186-B1 | USE OF OLIGOPEPTIDS FOR THE TREATMENT OF CEREBRAL DISORDERS | Fresenius AG (DE) | 1991-11-06 | — | — | EP | disclosed |
| EP-0234186-A1 | Use of oligopeptids for the treatment of cerebral disorders | Fresenius AG (DE) | 1987-09-02 | — | — | EP | disclosed |
| US-4051025-A | Preparative countercurrent chromatography with a slowly rotating helical tube array | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1977-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015813-A1 | Treatment of protein folding disorders | HSPA5, TTR, TUFM | ACE 2086/4885KDM4E 3502/4885MEN1 4065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.