Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 15/20 | 0.68 |
| ▸ | CACNA1D | Q01668 | 15/20 | 0.68 |
| ▸ | CACNA1S | Q13698 | 15/20 | 0.68 |
| ▸ | CACNA1C | Q13936 | 15/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | GUSB | P08236 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10358318 | 0.88 | CACNA1F (0.61) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL10915740 | 0.87 | CACNA1F (0.65) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL9871899 | 0.86 | CACNA1F (0.60) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL9476574 | 0.85 | CACNA1F (0.68) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL10358333 | 0.85 | CACNA1F (0.63) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL9475039 | 0.85 | CACNA1F (0.67) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL7271893 | 0.84 | CACNA1F (0.66) | CACNA1FCACNA1DCACNA1SCACNA1CLMNA | |
| SCHEMBL9871923 | 0.83 | ALDH1A1 (0.54) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL10357463 | 0.82 | CACNA1F (0.64) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL7272923 | 0.81 | CACNA1F (0.78) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071849-A | Antiinflammatory, antianginal agent | EGIS GYOGYSZERGYAR (HU) | 1991-12-10 | — | — | US | disclosed |