Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 6/20 | 0.41 |
| ▸ | HTR2C | P28335 | 6/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | LIG1 | P18858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26118236 | 0.87 | TSHR (0.53) | TSHRHPGDMAPK1HSD17B10CYP3A4 | |
| SCHEMBL11179875 | 0.81 | HTR2C (0.47) | TSHRHPGDMAPK1HSD17B10CYP3A4 | |
| SCHEMBL9671334 | 0.81 | TSHR (0.45) | TSHRHPGDMAPK1HSD17B10CYP3A4 | |
| SCHEMBL1903030 | 0.81 | TSHR (0.51) | TSHRHPGDMAPK1HSD17B10CYP3A4 | |
| SCHEMBL30216492 | 0.81 | TSHR (0.51) | TSHRHPGDMAPK1HSD17B10CYP3A4 | |
| SCHEMBL12004979 | 0.79 | TSHR (0.42) | TSHRHPGDMAPK1HSD17B10CYP3A4 | |
| SCHEMBL11144150 | 0.79 | MRGPRX4 (0.44) | TSHRHPGDMAPK1HSD17B10CYP3A4 | |
| SCHEMBL2060735 | 0.79 | MAPT (0.43) | TSHRHPGDMAPK1HSD17B10CYP3A4 | |
| SCHEMBL29520257 | 0.79 | MAPT (0.43) | TSHRHPGDMAPK1HSD17B10CYP3A4 | |
| SCHEMBL19817101 | 0.77 | TSHR (0.41) | TSHRHPGDMAPK1HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071468-A | Cereal selectivity | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1991-12-10 | — | — | US | disclosed |
| EP-0375076-A1 | Heterocyclic herbicides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-06-27 | — | — | EP | disclosed |