Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | PPARD | Q03181 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870006 | 1.00 | TSHR (0.48) | TSHRTHRBFNTAFNTBPGGT1B | |
| SCHEMBL11745674 | 0.87 | FNTA (0.42) | TSHRTHRBFNTAFNTBPGGT1B | |
| Oxalic Acid SCHEMBL27852342 | 0.84 | TSHR (0.59) | TSHRTHRBCYP3A4ALDH1A1CES2 | |
| SCHEMBL6522496 | 0.82 | FAAH (0.49) | THRBFNTAFNTBPGGT1BCES2 | |
| SCHEMBL6522490 | 0.82 | FAAH (0.49) | THRBFNTAFNTBPGGT1BCES2 | |
| SCHEMBL249764 | 0.82 | AKR1B1 (0.54) | TSHRALDH1A1AKR1B1MEN1KMT2A | |
| SCHEMBL476951 | 0.80 | AKR1B1 (0.52) | TSHRTHRBCYP3A4ALDH1A1AKR1B1 | |
| SCHEMBL2947287 | 0.80 | AKR1B1 (0.52) | TSHRTHRBCYP3A4ALDH1A1AKR1B1 | |
| SCHEMBL2948128 | 0.80 | AKR1B1 (0.52) | TSHRTHRBCYP3A4ALDH1A1AKR1B1 | |
| SCHEMBL11764726 | 0.80 | AKR1B1 (0.52) | TSHRALDH1A1AKR1B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253011-B1 | COPOLYMERS OF BENZOTRIAZOL MONOMERS WITH MALEIC OR FUMARIC ACID DERIVATIVES AND POLYMERIC MATERIAL COMPOSITIONS | MORISAWA & CO., LTD. (JP) | 1991-03-20 | — | — | EP | disclosed |
| EP-0253011-A1 | Copolymers of benzotriazol monomers with maleic or fumaric acid derivatives and polymeric material compositions | MORISAWA & CO., LTD. (JP) | 1988-01-20 | — | — | EP | disclosed |
| US-4686268-A | PHOTOSTABILITY | MORISAWA & CO., LTD. (JP) | 1987-08-11 | — | — | US | disclosed |